GLRT3 10mg
GLRT3 10mg
Couldn't load pickup availability
GLRT3 10mg
Get it as soon as -
30 Day Trial
30 Day Trial
We're confident you'll be happy with your order! In case things don't go as planned, you have 30 days to request a refund based on our return and refund policy.
Shipping & Processing
Shipping & Processing
Our shipping services are designed to be fast and reliable, ensuring your order is delivered promptly. Please allow 5-10 business days for delivery.
Track My Order
Track My Order
Once your order is shipped, we will provide you with a tracking number to monitor the progress of your shipment on our website or the shipping carrier's website. You can track your order here Track My Order
Each vial contains 10mg or 20mg of highly pure Retatrutide.
Retatrutide is classified as a triple glucagon hormone receptor agonist (GLP-1, GIP, and GCGR receptors), making it more effective for body fat mass reduction than its predecessor Semaglutide by targeting further receptors.
01The PureChain Standard
Purity And Documentation
Your results are only as good as the compound you start with.
Every vial is labelled with its compound, vial size and molecular weight, and ships for laboratory research use only. Third-party testing details will be published here.
Supplied for in-vitro laboratory research only. Not for human or veterinary use, and not intended to diagnose, treat, cure or prevent any disease.
- Size
- 10mg
- Form
- Lyophilized powder
- Storage
- −20 °C, protected from light
- Molar mass
- 4731.3 Da
About This Compound
About Retatrutide
Retatrutide is a synthetic peptide agonist that engages three receptors at once: the glucose-dependent insulinotropic polypeptide receptor, the glucagon-like peptide-1 receptor and the glucagon receptor. That is the whole design idea. Single-agonist compounds act on GLP-1R alone and dual agonists add GIPR; retatrutide adds the glucagon receptor as a third arm, which brings energy expenditure into the same molecule as the incretin effects. It is a research compound with no public PubChem structural record, so the formula and molecular mass below are taken from concurring published supplier data and cited under the structure.
Triple Incretin Receptor Agonist (GIP / GLP-1 / Glucagon)
Molecular Formula
Molecular Weight
Form
CAS Number
02Molecular Structure
The Retatrutide molecule
An illustrative atomic representation generated from the compound record, alongside its verified molecular data. The structure figure is schematic – not a measured conformation.
- C
- H
- N
- O
- S/P
No PubChem structural record exists for this compound. Molecular data from Selleck Chemicals and Cayman Chemical product data. View the source
By The Numbers
Retatrutide Research, By The Numbers
The figures that define Retatrutide and how it is being studied. For laboratory research use only.
Receptor Targets
GIP, GLP-1 and glucagon receptors engaged by one molecule
First Arm
The glucose-dependent insulinotropic polypeptide receptor
The Distinguishing Arm
The glucagon receptor, which dual agonists do not engage
Research Areas
- Incretin Receptor Pharmacology
- Metabolic Research
- Multi-Agonist Design
- Energy Expenditure Models
How It Works
How Retatrutide Works
The pathways Retatrutide acts on, and what each one does. Described from preclinical and receptor-pharmacology literature.
The Established Incretin Arm
The glucagon-like peptide-1 receptor is the best-characterised incretin target, studied for glucose-dependent insulin secretion and for signalling in the central nervous system. It is the arm retatrutide shares with every other compound in this class.
- Glucose-dependent insulin secretion in islet models
- Central nervous system receptor expression
- The common arm across all incretin agonists
The Second Incretin Receptor
GIP is the other incretin hormone, and adding its receptor is what separates dual agonists from single ones. Research on combined GIPR and GLP-1R engagement examines whether the two pathways act additively or through distinct mechanisms.
- The second incretin pathway alongside GLP-1
- Distinguishes dual agonists from single agonists
- Studied for additive versus distinct signalling
The Third Arm, And The Design Trade-Off
Glucagon receptor agonism is the arm unique to triple agonists. It is associated with energy expenditure and hepatic metabolism, and balancing it against the incretin arms is the central question in multi-agonist peptide design.
- The arm unique to the triple-agonist class
- Associated with energy expenditure and hepatic pathways
- Ratio balancing is the core design problem
Uses And Applications
What Retatrutide Is Researched For
The main areas Retatrutide is studied in, and the qualitative magnitudes reported alongside them.
Incretin Receptor Pharmacology
Used to study how a single molecule engaging three receptors compares against separate agonists for each.
Metabolic Research
Applied in preclinical metabolic models examining glucose handling, insulin secretion and energy balance.
Multi-Agonist Peptide Design
A reference compound for the design question of how to balance potency ratios across several receptors in one sequence.
Energy Expenditure Models
The glucagon receptor arm makes retatrutide the tool of choice where energy expenditure, not just incretin signalling, is the variable under study.
Compound Information
Full Specification
| Chemical Name | Retatrutide (LY3437943) |
|---|---|
| Molecular Weight | 4731.3 Da |
| Molecular Formula | C221H342N46O68 |
| CAS Number | 2381089-83-2 |
| Form | Lyophilized powder |
| Solubility | Water-soluble |
| Storage | Store lyophilized at −20 °C, protected from light and moisture |
| Vial Size | 10mg |
| Structural Record | No PubChem entry; values from published reference data |
FAQ
Common Questions About Retatrutide
What Is Retatrutide?
A synthetic peptide agonist at three receptors – GIP, GLP-1 and glucagon – also referred to as LY3437943. It is supplied here as a research compound.
Where Do The Molecular Figures On This Page Come From?
Retatrutide has no public PubChem structural record. The formula and molecular mass shown are taken from published supplier reference data, and the source is cited directly under the structure. Every other compound in this catalogue is sourced from PubChem and cites its CID.
How Does A Triple Agonist Differ From A Dual Agonist?
By the third receptor. Dual agonists engage GIP and GLP-1 receptors; a triple agonist adds the glucagon receptor, which brings energy expenditure pathways into the same molecule.
What Are Incretins?
Gut hormones released in response to food that stimulate insulin secretion in a glucose-dependent way. GLP-1 and GIP are the two principal incretins in humans.
Is Retatrutide Approved For Human Use?
No. It is supplied as a research chemical for in-vitro laboratory work only, and is not supplied for human or veterinary use.
How Should Research-Grade Retatrutide Be Stored?
Store the lyophilized powder at −20 °C, protected from light and moisture, and refrigerate after reconstitution. Aliquot to avoid repeated freeze-thaw cycles.
Feedback
WHAT OUR CUSTOMERS HAVE TO SAY...
"Been using PureChain Labs for 9 months now. In my opinion, it's the best source in Canada. Quality product every time and gives me the best results. Also the communication is second to none, I get a response in minutes usually. Overall extremely happy with the service and product they provide."
"A+ service and communication. Delivery is always quick and packaged safe and sound... I love how they are transparent and you know what your getting and for using a new source for the first time that's a huge relief."
"Took a month but hair felt thicker at roots, gave me hope after months of thinning, they definitely sell quality peptides."
Not for human or veterinary use. For in-vitro laboratory research only. These statements have not been evaluated by the FDA or Health Canada; this product is not intended to diagnose, treat, cure or prevent any disease.